Rest Study

Help researchers at the San Francisco VA Medical Center and UCSF learn more about a treatment for Posttraumatic Stress Disorder.

What is PTSD? 
Posttraumatic Stress Disorder (PTSD) is a set of psychological symptoms that may impact a person after experiencing a life-threatening event such as assault, natural disaster, war, or combat. Common symptoms include:

  • Difficulty falling and staying asleep
  • Nightmares or unwanted memories of a traumatic experience
  • Jumpiness and being easily startled
  • Avoidance of situations that remind you of a traumatic experience
  • Feeling tense, on-guard, irritable, or lose your cool over minor everyday things
What is the study about?
This clinical trial is testing the effect of doxazosin, an FDA-approved medication which may help alleviate symptoms of Posttraumatic Stress Disorder including distressing dreams. Study participation includes seven nights of home sleep monitoring, and up to eight weeks of treatment and assessment. During that time, participants will be closely monitored by the study physician.

Where is the study located?
The study is located at the San Francisco VA Medical Center.

How do I know if I qualify?
If you are between the ages of 18 and 69 with some of the above symptoms including upsetting dreams or sleep difficulties following a life threatening event, you may be a good candidate.  Please know that you may qualify even if you have never been diagnosed with PTSD. 
How do I get started?
We will ask you some questions over the phone, and if you are a potential match for the study, we will invite you to participate in a confidential clinical interview.  Participants will be screened for eligibility and medical safety.  Compensation for completing the study is up to $430.

Please call or email to learn more details
(415) 221-4810 ext 3809