Julius M. Guccione, Ph.D.
Research Scientist, Surgical Service, SFVAMC
Associate Professor of Surgery, UCSF
Email: Julius.Guccione@va.gov
Measuring and Improving Cardiac Function through Bioengineering
Dr. Guccione studies the role of stem cell transplantation on the biophysics of cardiac function and the use of mechanical engineering principles in the diagnosis and treatment of cardiac disease. He is Co-director of the SFVAMC Cardiac Biomechanics Laboratory, which uses a combination of mathematical modeling and animal experiments to determine the effect of cardiac surgery on left ventricular function and remodeling. He is also a Core member of the UCB/UCSF Joint Graduate Group in Bioengineering. Current projects involve testing and validating a software tool for determining myocardial material properties in vivo using cardiac catheterization and magnetic resonance imaging, and determining the effects of three different surgical treatments on function and regional mechanics in sheep.
Dr. Guccione is co-editor of Computational Cardiovascular Mechanics, which is the first book to comprehensively address heart failure from a computational modeling perspective.
Guccione JM, Kassab GS, Ratcliffe MB (Eds.). 2010. Computational Cardiovascular Mechanics: Modeling and Applications in Heart Failure, 1st Edition. Springer US.
Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Hsu EW, Saloner DA,
Guccione JM. 2008. Magnetic resonance imaging-based finite element
stress analysis after linear repair of left ventricular aneurysm. J Thorac Cardiovasc Surg 135(5):1094-102,1102.e1-2.
Zhang P, Guccione JM, Nicholas SI, Walker JC, Crawford PC, Shamal A, Acevedo-Bolton G, Guttman MA, Ozturk C, McVeigh ER, Saloner DA, Wallace AW, Ratcliffe MB. 2007. Endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm increases systolic circumferential shortening in sheep. J Thorac Cardiovasc Surg 134(4):1017-24.
