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NCIRE-The Veterans Health Research Institute is the leading private nonprofit institute devoted to Veterans health research in the United States. Our mission is to advance Veterans health through research.

We support the work of some of the nation's foremost physicians and scientists at the San Francisco Veterans Affairs Medical Center, the premier biomedical research facility in the VA system. All have faculty appointments at the University of California, San Francisco, which has its own proud traditions of research and patient care. We also partner with the U.S. Department of Defense to support health research on behalf of our men and women in the Armed Forces.

Those who have served in uniform have given their best for their country. In return, we believe that they deserve nothing less than the best health care research we can provide.

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Sophia Vinogradov, MD

Associate Chief of Staff for Mental Health, SFVAMC
Professor and Vice-Chair, Department of Psychiatry, UCSF


Schizophrenia and Mental Health

Dr. Vinogradov studies how the brain malfunctions in schizophrenia, a devastating psychiatric illness that strikes young adults in their prime.  She is also a leader in the next wave of treatment and prevention of schizophrenia, using techniques of  intensive computer-based training exercises to correct the brain information-processing abnormalities of the illness.  This translational science work involves collaborations with neuroscientists and clinicians, and includes the use of brain imaging techniques to understand how the brain responds to the intervention.  She has also founded a clinic at UCSF that aims to identify adolescents who show risk signs for developing schizophrenia and to intervene to prevent the onset of the illness. Dr. Vinogradov's work has been seminal in the development of a whole new area of treatment for serious psychiatric illness, using computerized cognitive training to target the neural system dysfunction that characterize behavioral disorders. These "cognitive neurotherapeutic" applications are being studied in addictions, in PTSD, and in TBI, and are the basis for innovative collaborative relationships with the interactive software industry (see

To see Dr. Vinogradov on Pub Med, click here.