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Research at NCIRE

NCIRE-The Veterans Health Research Institute is the leading private nonprofit institute devoted to Veterans health research in the United States. Our mission is to advance Veterans health through research.

We support the work of some of the nation's foremost physicians and scientists at the San Francisco Veterans Affairs Medical Center, the premier biomedical research facility in the VA system. All have faculty appointments at the University of California, San Francisco, which has its own proud traditions of research and patient care. We also partner with the U.S. Department of Defense to support health research on behalf of our men and women in the Armed Forces.

Those who have served in uniform have given their best for their country. In return, we believe that they deserve nothing less than the best health care research we can provide.

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Raj Dahiya, PhD

Research Scientist, Medical Research Service, SFVAHCS
Professor of Urology, UCSF
Email: rdahiya@gmail.com

Age, Race, and Prostate Cancer

Dr. Dahiya's research focuses on ways to identify and characterize genes that are epigenetically (reversibly) silenced in age-related prostate cancer. These genes may be used for early diagnosis and prognosis of the disease. Another use is to identify possible genetic and epigenetic risk factors for race-related prostate cancer. In one study, Dr. Dahiya investigated whether over- expression of the genes cytochrome P450 1A1 and cytochrome P450 1B1 are risk factors for race-related prostate cancer. In another recent study, Dr. Dahiya reported that the tumor suppressor gene GSTPI is inactivated at a significantly higher rate in African American prostate cancer patients than in Caucasian patients. These mechanisms provide potentially novel approaches to the management of prostate cancer.

To learn more about Dr. Dahiya and his work, click here.

To see Dr. Dahiya on Pub Med, click here.