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Research at NCIRE

NCIRE-The Veterans Health Research Institute is the leading private nonprofit institute devoted to Veterans health research in the United States. Our mission is to advance Veterans health through research.

We support the work of some of the nation's foremost physicians and scientists at the San Francisco Veterans Affairs Medical Center, the premier biomedical research facility in the VA system. All have faculty appointments at the University of California, San Francisco, which has its own proud traditions of research and patient care. We also partner with the U.S. Department of Defense to support health research on behalf of our men and women in the Armed Forces.

Those who have served in uniform have given their best for their country. In return, we believe that they deserve nothing less than the best health care research we can provide.

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Pratik Mukherjee, MD, PhD

Professor of Radiology and Biomedical Imaging, Bioengineering and Therapeutic Sciences, UCSF

Mapping Human Brain Structural and Functional Connectivity

Pratik Mukherjee, MD, PhD is Professor of Radiology and Biomedical Imaging, Bioengineering and Therapeutic Sciences at the University of California, San Francisco (UCSF).  He is a practicing clinical attending neuroradiologist at UCSF and directs a laboratory at the Center for Molecular and Functional Imaging in the UCSF Dept. of Radiology and Biomedical Imaging.  Dr. Mukherjee is also the Director of the Center for Imaging of Neurodegenerative Diseases (CIND) at the San Francisco Veterans Affairs Medical Center.

Dr. Mukherjee received his B.A. in Computer Science and Psychology from Yale University, his M.D. from Cornell University and his Ph.D. in Computational Neuroscience from the Rockefeller University in New York City.  He completed a Radiology residency and Neuroradiology fellowship at Washington University at St. Louis before the joining the faculty at UCSF in 2002.

Dr. Mukherjee currently serves as the Chair of Neuroradiology and Head/Neck Imaging for the Scientific Program Committee of the Radiological Society of North America (RSNA).   For the past 3 years, Dr. Mukherjee has served as co-Chair of the Research Committee for the American Society of Neuroradiology (ASNR).  He has also served as the Chair of Neuro Education for the Annual Meeting Program Committee of the International Society for Magnetic Resonance in Medicine (ISMRM).

Dr. Mukherjee’s research has focused on the technical development and basic and clinical neuroscience applications of advanced imaging methods for mapping structure and function in the human brain.  He has made many of the initial observations of human white matter development in newborns and children using diffusion tensor imaging (DTI).  He also led the development of more advanced techniques known collectively as high angular resolution diffusion imaging (HARDI) for surmounting the limitations of DTI for characterizing regions of complex white matter architecture.   Currently, Dr. Mukherjee’s primary clinical research effort is the study of traumatic brain injury (TBI) using advanced imaging tools, including DTI, functional MRI (fMRI) and magnetoencephalography (MEG).  Both diffusion tractography and resting state fMRI technology have been used in his lab to map the connectivity of human brain networks in pathologic conditions such as brain malformations and brain injury.

To see dr. Mukherjee on PubMed, click here.