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Research at NCIRE

NCIRE-The Veterans Health Research Institute is the leading private nonprofit institute devoted to Veterans health research in the United States. Our mission is to advance Veterans health through research.

We support the work of some of the nation's foremost physicians and scientists at the San Francisco Veterans Affairs Medical Center, the premier biomedical research facility in the VA system. All have faculty appointments at the University of California, San Francisco, which has its own proud traditions of research and patient care. We also partner with the U.S. Department of Defense to support health research on behalf of our men and women in the Armed Forces.

Those who have served in uniform have given their best for their country. In return, we believe that they deserve nothing less than the best health care research we can provide.

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Phyllis C. Tien, MD

Staff Physician, Medical Service, SFVAMC
Professor of Medicine, UCSF

Chronic viral infections (HIV and HCV) and its metabolic/inflammatory consequences to organ injury

Dr. Tien is a clinical translational researcher who investigates chronic viral infections, specifically HIV and HCV, and their metabolic and inflammatory consequences on long term organ injury (e.g. liver, bone and vascular injury). As part of this work, she also studies novel non-invasive techniques to estimate steatosis and fibrosis using magnetic resonance (MR) imaging and ultrasound-based transient elastography as well as novel CT and MR imaging methods to measure bone and vascular injury. She is the Principal Investigator of an NIH funded R01 study to investigate the link between visceral adiposity, HIV, and HCV to the pathogenesis of hepatic steatosis and fibrosis and an NIH funded K24 award to mentor early career investigators to examine the effects of HIV/HCV coinfection on liver, bone and vascular injury. She is also one of three Principal Investigators of the Northern California site of the Women's Interagency HIV Study (WIHS), which is the largest and longest running prospective cohort of the progression of HIV infection in women in the US.

She serves as the Chair of the WIHS Executive Committee, and is a member of the Department of Health and Human Services Antiretroviral Therapy Guidelines Panel for Adults and Adolescents and the NIH AIDS Clinical Epidemiology Study Section.

To see Dr. Tien on Pub Med, click here.