NCIRE - The Veterans Health Research Institute Home  |  Sitemap  |  Intranet  |  UltiPro   Visit our Facebook page  Visit our Twitter page  Visit our LinkedIn page

Give Now
About NCIRE Participate in Research Support Our Mission Careers at NCIRE Contact Us
Veterans Health
Research at NCIRE

NCIRE-The Veterans Health Research Institute is the leading private nonprofit institute devoted to Veterans health research in the United States. Our mission is to advance Veterans health through research.

We support the work of some of the nation's foremost physicians and scientists at the San Francisco Veterans Affairs Medical Center, the premier biomedical research facility in the VA system. All have faculty appointments at the University of California, San Francisco, which has its own proud traditions of research and patient care. We also partner with the U.S. Department of Defense to support health research on behalf of our men and women in the Armed Forces.

Those who have served in uniform have given their best for their country. In return, we believe that they deserve nothing less than the best health care research we can provide.

Contact Us
Email NCIRE
Give Now
Michael W. Weiner, MD

Principal Investigator of the Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Brain Health Registry (BHR); Professor, Department of Radiology, Neurology, Psychiatry and Medicine, UCSF
Email: michael.weiner@ucsf.edu

Diagnosing Neurodegenerative Disorders using Advanced Magnetic Resonance Techniques

Dr. Weiner has been doing research for over 45 years and is the Principal Investigator of the Alzheimer's Disease Neuroimaging Initiative (ADNI), a 10-year national longitudinal study of over 1,500 subjects which is aimed at validating biomarkers for Alzheimer’s disease. He has also launched the BrainHealthRegistry.org which is an internet based registry with the overall goal of accelerating development of effective treatments for brain diseases. This website registry recruits, screens, and longitudinally monitors brain function on thousands of subjects all over the USA. Dr. Weiner’s overall research goal is to participate in the development of effective treatments and methods for early detection of Alzheimer's disease and other brain disorders. In 1980, Dr. Weiner was one of the first investigators to use nuclear magnetic resonance to investigate the metabolism of organs inside a living animal. This technique subsequently became magnetic resonance spectroscopy (MRS). In 1988, his group used MRS to show that the amino acid N acetyl aspartate (NAA), a marker of healthy nerve cells, is reduced in the epileptic focus in the brain. This marker is now used to help identify the epileptic focus prior to surgery in epilepsy patients. In 2004, Dr. Weiner's group reported that reduced NAA predicts development of Alzheimer's disease in mildly impaired elderly subjects. They have also demonstrated that brain blood flow is reduced in Alzheimer's disease and in patients with mild impairment. Dr Weiner has over 650 published articles. In 2006, Dr. Weiner received the William S. Middleton Award, the highest scientific honor bestowed by the Department of Veterans Affairs. In 2010 he was named one of the “Rock Stars of Science”. He also received the Gold Medal of Paul Sabatier University and the City of Toulouse, France.  In 2011 he received the Ronald and Nancy Reagan Research Award from the Alzheimer’s Association, and in 2013 he received the Potamkin Award from the American Academy of Neurology and the American Brain Foundation.

To see Dr. Weiner on Pub Med, click here.